Albert Hammond Jr and Doves man Jimi Goodwin (pictured) are among the acts who will play for as the city's East Wing venue, which is part of the Brighton Centre, on the festival's opening night.
The full Q Stage, which is open between 7pm-11pm (BST), is as follows:
Albert Hammond Jr. Jimi Goodwin Little Matador NEØV Nothing But Thieves
The Great Escape takes place across venues in Brighton between 8-10 May. For the full festival line-up, and the latest ticket news head Greatescapefestival.com with the likes of Kelis, Wild Beasts and These New Puritans leading a diverse bill of artists.